{
  "id": "ark:/99999/dp-target-product-profiles-for-malaria-diagnostics.v1",
  "concept": "ark:/99999/dp-target-product-profiles-for-malaria-diagnostics",
  "url": "https://datasetpapers.com/papers/malaria-diagnostic-tpp-characterization/",
  "title": "Structured characterization of malaria diagnostic Target Product Profile requirements across two use-cases",
  "source_dataset": {
    "title": "Target product profiles for malaria diagnostics.",
    "doi": "10.1371/journal.pmed.1000396.t001",
    "license": "CC BY 4.0"
  },
  "verification": {
    "method": "re_execution",
    "status": "matched",
    "reproduced": true,
    "ran_at": "2026-07-13T14:11:33Z",
    "record": "verification.json"
  },
  "gate": {
    "passed": true,
    "version": "gate-0.1",
    "novelty_grade": "C",
    "failed": []
  },
  "claims": [
    {
      "id": "ark:/99999/dp-target-product-profiles-for-malaria-diagnostics.v1/claim-1",
      "n": 1,
      "triple": {
        "subject": "the two malaria diagnostic use-cases (case management in elimination vs screening/surveillance)",
        "predicate": "do not differ significantly in priority-tier (Essential/Desirable/Optional) composition",
        "object": "overall assignment of requirement priority tiers"
      },
      "assertion_text": "Across 62 tagged requirement items, the priority-tier composition (E/D/O) does not differ significantly between the two use-cases (Freeman-Halton exact p = 0.59; Holm-corrected p = 0.81; chi-square = 2.00, reference only; Cramer's V = 0.18; min expected cell count 0.97). A presence/absence sensitivity analysis is concordant (exact p = 0.58, V = 0.19).",
      "novelty_grade": "D",
      "mode": "null_result",
      "confidence": 0.9,
      "self_reported_status": "unverified",
      "independent_reexecution": "matched",
      "entities": [],
      "relations": [
        {
          "predicate": "supportedByEvidence",
          "target": "ark:/99999/dp-target-product-profiles-for-malaria-diagnostics.v1/fig-1"
        },
        {
          "predicate": "supportedByEvidence",
          "target": "ark:/99999/dp-target-product-profiles-for-malaria-diagnostics.v1/tbl-1"
        },
        {
          "predicate": "supportedByEvidence",
          "target": "ark:/99999/dp-target-product-profiles-for-malaria-diagnostics.v1/analysis"
        },
        {
          "predicate": "wasDerivedFrom",
          "target": "https://doi.org/10.1371/journal.pmed.1000396.t001"
        },
        {
          "predicate": "isPartOf",
          "target": "ark:/99999/dp-target-product-profiles-for-malaria-diagnostics.v1"
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      ]
    },
    {
      "id": "ark:/99999/dp-target-product-profiles-for-malaria-diagnostics.v1/claim-2",
      "n": 2,
      "triple": {
        "subject": "per-criterion diagnostic requirements between the two use-cases",
        "predicate": "differ in wording about as often as not, with no significant departure from parity",
        "object": "identical-vs-differing status of each of 23 criteria"
      },
      "assertion_text": "Of 23 substantive criteria, 9 are identical and 14 differ between use-cases (proportion differing = 0.61, Wilson 95% CI 0.41-0.78); this is not distinguishable from one-half (exact binomial p = 0.40; Holm-corrected p = 0.81). A normalized-text sensitivity check gives the identical count (14 differing).",
      "novelty_grade": "D",
      "mode": "null_result",
      "confidence": 0.9,
      "self_reported_status": "unverified",
      "independent_reexecution": "matched",
      "entities": [],
      "relations": [
        {
          "predicate": "supportedByEvidence",
          "target": "ark:/99999/dp-target-product-profiles-for-malaria-diagnostics.v1/fig-2"
        },
        {
          "predicate": "supportedByEvidence",
          "target": "ark:/99999/dp-target-product-profiles-for-malaria-diagnostics.v1/tbl-2"
        },
        {
          "predicate": "supportedByEvidence",
          "target": "ark:/99999/dp-target-product-profiles-for-malaria-diagnostics.v1/analysis"
        },
        {
          "predicate": "wasDerivedFrom",
          "target": "https://doi.org/10.1371/journal.pmed.1000396.t001"
        },
        {
          "predicate": "isPartOf",
          "target": "ark:/99999/dp-target-product-profiles-for-malaria-diagnostics.v1"
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      ]
    },
    {
      "id": "ark:/99999/dp-target-product-profiles-for-malaria-diagnostics.v1/claim-3",
      "n": 3,
      "triple": {
        "subject": "the most-stringent required tier per criterion",
        "predicate": "is identical across use-cases for the large majority of criteria, diverging only in domain-specific ways",
        "object": "ordinal stringency (Essential>Desirable>Optional>Not required) of each criterion in each use-case"
      },
      "assertion_text": "On an ordinal stringency scale, the two use-cases assign the same most-stringent tier on 19 of 23 criteria. The screening/surveillance use-case is more stringent on 3 criteria (genotyping, gametocyte detection, hypnozoite detection) and case management is more stringent on 1 (instrumentation and laboratory infrastructure). This is a descriptive count, not a tested hypothesis, and no causal interpretation is made.",
      "novelty_grade": "C",
      "mode": "descriptive",
      "confidence": 0.95,
      "self_reported_status": "unverified",
      "independent_reexecution": "matched",
      "entities": [],
      "relations": [
        {
          "predicate": "supportedByEvidence",
          "target": "ark:/99999/dp-target-product-profiles-for-malaria-diagnostics.v1/fig-3"
        },
        {
          "predicate": "supportedByEvidence",
          "target": "ark:/99999/dp-target-product-profiles-for-malaria-diagnostics.v1/tbl-3"
        },
        {
          "predicate": "supportedByEvidence",
          "target": "ark:/99999/dp-target-product-profiles-for-malaria-diagnostics.v1/analysis"
        },
        {
          "predicate": "wasDerivedFrom",
          "target": "https://doi.org/10.1371/journal.pmed.1000396.t001"
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        {
          "predicate": "isPartOf",
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}